Neuroendocrine Effects of TBI

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In the Journal of Neuropsychiatry and Clinical Neuroscience 19; 4, Fall 2007, Micol Rothman, MD and his co-authors presented their research on neuroendocrine dysfunction after traumatic brain injury,( Neuroendocrine Effects of TBI ). Rothman and his fellow researchers state that neuroendocrine problems are often under-diagnosed and under-treated and may play a large role in determining the rate of recovery.Dr. Rothman and team report that screening for neuroendocrine deficits is not done routinely and the adverse effects of hormonal deficits include delaying physical and cognitive recovery are not adequately considered. The study examined Anterior Pituitary, Adrenocorticotropin (ACTH) and Thyrotropin Deficiencies as well as Prolactin Dysregulation. Dr. Rothman's study suggests evaluating patients early in their recovery and considering the neuroendocrine issues in formulating acute treatment interventions. Rothman's article recognizes that clinical research in this area may prove difficult, but that consideration of hormonal replacement therapies may boost recovery, especially in severe injuries.

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