Cell therapy following traumatic brain injury (TBI) contributes to speedier and better quality recoveries in children according to new research by The University of Texas Health Science Center at Houston (UTHealth) Medical School.
The study, published in the most recent issue of Pediatric Critical Care Medicine, showed the use of cell therapy can reduce the amount of therapeutic interventions needed to properly treat a patient, as well as the amount of time a child recovering from TBI spends in neurointensive care.
Between the years of 2000 and 2008, TBI patients at Children’s Memorial Hermann Hospital were split into two groups. One group contained children who received autologous bone marrow stem cells as part of a pilot study. The other group did not receive cell therapy.
For the study, the researchers used the Pediatric Intensity Level of Therapy to measure the level of therapeutic intensity used to reduce the cranial pressure below the danger zone. Researchers observed those who received the stem cells showed a significant reduction in the first 24 hours following treatment through the first week. Those who did not receive the stem cells spent nearly twice the duration in neurointensitive care, spending an average 15.6 days compared to 8.2.