Clazosentan, in an animal trial, has been shown to be effective in increasing the blood flow to the hippocampus following TBI. The positive results of the animal study will hopefully move the study forward to human application. We know that intervention immediately following TBI can reduce injury severity and researchers continue to look for drugs which can intervene with the biological processes which occur immediately after the injury. Another investigational agent going through drug trials is the female hormone Progesterone which has been shown to reduce the spasms of electrical activity in the brain which accounts for cell death in the wake of an injury.
Click here to read the story from the LA Times about Clazosentan
Tag Lines: traumatic brain injury; Clazosentan; progesterone; reducing TBI severity